NFL Nation reporters assess the?biggest injuries across the league for Week 1.NFC East | NFC North | NFC South | NFC West AFC East | AFC North| AFC South | AFC WestNFC EASTDallas CowboysLinebacker Sean Lee was held out of practice last week because of soreness in his surgically repaired left knee, but the time off was designed to have him ready for this week. He played just 29 snaps in the preseason but he said he feels ready to go, and the Cowboys will need Lee to be at his best. He is their best playmaker defensively and knows how to get the rest of the defense in the right spots, which is a must against a veteran quarterback like Eli Manning. In two games against New York last season, Lee?had 18 tackles. -- Todd ArcherNew York GiantsRookie free safety Darian Thompson missed the previous two weeks with a shoulder injury, but he practiced Wednesday in a limited capacity. Thompson is wearing a harness and is expected to play -- and likely start -- Sunday against the Cowboys. The key is to see how he does in Thursdays fully padded practice. If Thompson cant play, Nat Berhe has been taking first-team reps in his place. Overall, the Giants are relatively healthy. All 53 players on their active roster practiced Wednesday and are expected to play in the opener. The Giants also didnt lose a projected starter to injury this spring or summer. -- Jordan RaananPhiladelphia EaglesRookie quarterback Carson Wentz has been cleared for action after sitting out most of the preseason with a hairline rib fracture. Coach Doug Pederson announced that every Eagles player practiced Wednesday, including defensive end Vinny Curry, who was eased in after missing some time with a knee injury. Wide receiver?Jordan Matthews missed the preseason with a knee injury of his own, but he is expected to be full go. The Eagles are in good health overall heading into Week 1. -- Tim McManusWashington RedskinsRunning back Matt Jones was full go in practice Wednesday and didnt need to wear a yellow no-contact jersey like he had to on Monday. The expectation remains that Jones will play Monday vs. Pittsburgh after missing two weeks of practice with a sprained left shoulder. Rookie wide receiver Josh Doctson practiced Monday, but he was limited Wednesday and its uncertain if hell play against the Steelers as he returns from Achilles tendonitis. -- John KeimNFC NORTHChicago BearsThe primary concern is guard Kyle Longs (shoulder) health, but he practiced on Monday and Wednesday and looks on track to play against the Texans. Of course, the great unknown is how Longs shoulder reacts when faced with live contact. Cornerback Tracy Porter passed the NFLs concussion protocol and pronounced himself good to go for Week 1, but Kyle Fullers status is more difficult to predict. Fuller is doing some work at practice, but is only a couple weeks removed from arthroscopic knee surgery. -- Jeff DickersonDetroit LionsThe Lions are almost fully healthy heading into their season opener against Indianapolis. While tight end Eric Ebron (ankle) has been a question mark over the past few weeks, he took part in practice Monday and Wednesday. This is a good sign hell be available after not playing at all in the preseason. The Lions need him, too, because their tight end depth after him is questionable. -- Michael RothsteinGreen Bay PackersWide receiver?Jordy Nelson isnt even on the injury report this week, so how can he be an injury question? Well, it has been nearly 13 months since he has been on a game field, and that was when he tore the ACL in his right knee at Pittsburgh. Will the 31-year-old be able to return to his Pro Bowl form from 2014? He says there are no limitations on his knee, and coach Mike McCarthy said Nelson will be full bore for the opener in Jacksonville. But considering Nelson didnt play a single snap in a preseason game this year, its hard to know what impact t