NEW YORK -- The business end of the seasons last Grand Slam is approaching and, thankfully, most of the top seeds are still alive. Wednesday offers four fascinating, mostly marquee matches, with the winners advancing to the semifinals:Watch every matchAt 11 a.m. ET, all play on the outer courts (juniors and doubles) will begin on ESPN3. Click to watch?multicam.?At noon ET, ESPN and WatchESPN begin coverage of Wednesdays quarterfinal matches. Click to watch.?To view starting times of upcoming days at the US Open, click here.?Live scoringOur real-time scoreboard, updated stats and social handles can be found on one spot: US Open CourtCast.?Schedules?Heres a schedule of whos playing Wednesday. Click here.Wednesday key matchesNo. 10 Karolina Pliskova versus Ana Konjuh, noon ET on Arthur Ashe Stadium (Watch)This one is the outlier. Konjuh, an 18-year-old from Croatia, has been a revelation, knocking off No. 20 seed Kiki Bertens in the first round and No. 4 Agnieszka Radwanska in the fourth. The WTAs No. 92-ranked player only made it to the second round of the seasons previous three majors. Pliskova will be a tougher out, however. Her 29 aces are tied for second among women, and she took out No. 6 seed Venus Williams in a terrific three-set match in the fourth round. Pliskova and Konjuh have never met.No. 2 Andy Murray versus No. 6 Kei Nishikori, following Pliskova-Konjuh (Watch)This was the quarter, based on seeds, that the draw foretold. After a scratchy third-round win over Paolo Lorenzi, Murray crushed lackadaisical No. 22 seed Grigor Dimitrov in the fourth round, dropping only five games. Nishikori, a finalist here in 2014, has played three four-set matches. Murray leads the head-to-head 7-1, including wins in their past four matchups. Murray scorched Nishikori in Rio de Janeiro a few weeks ago.No. 1 Serena Williams versus No. 5 Simona Halep, 7 p.m. ET on Arthur Ashe Stadium (Watch)This is another quarter bracket that played true to form. Williams cant remember ever serving so consistently, and she has yet to lose a set in her quest to keep the No. 1 ranking. Halep has dropped only one set. She was impressive in dispatching No. 11 seed Carla Suarez Navarro in the fourth round. The history between these two has been one-sided: Serena holds a 7-1 career edge, most recently beating Halep in straight sets at Indian Wells in March. In their only Grand Slam meeting, at Wimbledon in 2011, Serena needed three sets to prevail.No. 3 Stan Wawrinka vs. Juan Martin del Potro, following Williams-Halep (Watch)Although del Potro -- in the midst of yet another comeback from wrist surgery -- is unseeded here, he has beaten the two-time Grand Slam champion in four of six previous matches. Del Potros most recent victory, a few months ago at Wimbledon, was significant. He won in four sets, and it was the beginning of his confident surge back into the elite level of tennis. Del Potro won this tournament seven years ago, his only major victory to date. Julian Edelman Youth Jersey . It might not have mattered. While the Dodgers are preparing for the playoffs, the Padres showed their future has promise behind two rookies. Tom Brady Patriots Jersey . Robredo, ranked No. 16, bounced back from an upset loss to Leonardo Mayer in the second round of the Royal Guard Open in Chile last week to down Carreno Busta in 1 hour, 25 minutes. On a day filled mostly with qualifying matches, fifth-seeded Marcel Granollers of Spain also entered the second with a 7-5, 3-6, 6-2 win over Aljaz Bedene of Slovenia, while Guido Pella of Argentina defeated Guillermo Garcia-Lopez of Spain 7-6 (6), 6-4 to advance. https://www.patriotssportsgoods.com/Womens-Stephon-Gilmore-Inverted-Jersey/ . According to a report from the Vancouver Province, the Lions are expected to replace former DC Rich Stubler with defensive backs coach Mark Washington. Rob Gronkowski Patriots Jersey . The news was first reported on Gonzalezs Twitter account and confirmed by the Rockies. Gonzalez has a six-week window before position players have their first workout at spring training in Arizona. Jarrett Stidham Youth Jersey .com) - Following a late-game loss to the reigning NBA champs, the Toronto Raptors will look to sustain their recent high-level play as they travel to Indiana to take on the Pacers. Ferrari Academy driver Charles Leclerc says the late Jules Bianchi was on his mind when he took to the track for his first test with Ferrari on Tuesday.After impressing on his F1 debut with Haas during first practice for the British Grand Prix, Leclerc secured a test day with Ferrari on Tuesday. After finishing his track time at Silverstone, Leclerc opened up about his relationship with his mentor Bianchi, who died last year from injuries sustained at the 2014 Japanese Grand Prix.I knew him from when I was really, really young, he said. He was my godfather and he helped me with most of things in racing.Obviously now its hard without him because he always helped me, and I miss his hellp.ddddddddddddHe advised me really well in the past, and all his comments he gave me in the past I keep them in mind and try not to make the errors he told me not to do.Bianchi was also a member of the Ferrari Driver Academy up until the time of his death and Leclerc is sure he would have become a Ferrari race driver if he was still alive.Yeah. Jules was one of the talents who would have gone there if the things that happened hadnt have happened, he said. But Im definitely confident the driver academy will have someone who will make it into the top team. ' ' '