NEW YORK -- The last time the New England Patriots opened a season without Tom Brady under center, few could have imagined what the young quarterback would become.It was 2001, when Drew Bledsoe started the first two games before suffering a serious chest injury -- opening the door for a second-year quarterback from Michigan drafted 199th overall. Brady led the Patriots to a Super Bowl victory that season, the first of four titles so far that he and coach Bill Belichick have won with New England.Fifteen years and tons of accolades later, Brady will have to sit out the first four games of this season for his role in the Deflategate scandal.Ill be excited to be back when Im back, he said, and Ill be cheering our team on, hoping they can go out and win every game.A lot of that, of course, will be up to how Jimmy Garoppolo performs in Bradys absence.The 2014 second-rounder out of Eastern Illinois will go back to the sideline when Brady returns, but Garoppolo could set the tone for the Patriots in the AFC East. New England has won the division seven straight years, and 12 of the last 13 -- with the only stumble coming in 2008, when Brady tore knee ligaments in the season opener.The best bet for the New York Jets, Miami Dolphins and Buffalo Bills might be to make their move early.Youve got to win your division games, Jets wide receiver Eric Decker said. With Brady being suspended four games, I think it makes the division up for grabs.Both Buffalo and Miami play New England in the first four weeks, but none of the Patriots division rivals is throwing any dirt on its rival just yet.Hes important for those guys, but if youve been watching, you can see theyre still doing some of the same things, Bills safety Corey Graham said. Theyre playing very well. Its a great system to be in. Dont get me wrong, Tom Bradys one of the greatest quarterbacks, but I feel like the backup guy can more than get the job done.While Bradys absence might be the biggest story line, here are other things to know about the AFC East:BRADYS BUNCH: The Patriots offense has a few major question marks beyond the quarterback. Theres uncertainty at running back with projected starter Dion Lewis working his way back from knee surgery, so it might be a committee approach -- as Belichick has often done. Tight end Rob Gronkowski has been sidelined since Aug. 15 with an undisclosed ailment, while wide receivers Julian Edelman (left foot) and Danny Amendola (left knee, bone spurs in ankle) are working their way back from injuries.The offensive line will have a new look with David Andrews taking over at center and rookie Joe Thuney, a third-rounder, likely starting at left guard.MORE FITZ MAGIC?: It took the Jets and quarterback Ryan Fitzpatrick the entire offseason to settle a contract stalemate, but it was a reunion both sides knew was inevitable. Fitzpatrick took over last summer when Geno Smith had his jaw broken by a punch from a teammate and went on to set a franchise record with 31 touchdown passes. Brandon Marshall broke team marks with 109 catches and 1,502 yards receiving while scoring 14 TDs, and Decker had 80 receptions for 1,027 yards and 12 TDs. The addition of versatile running back Matt Forte should make the offense even more dangerous.The key for the Jets, though, is getting through their rough first half of the schedule. They have six road games in the first nine weeks, and five of their first six opponents made the playoffs last season.GASE ON THE CASE: Adam Gase is the NFLs youngest head coach at 38, but his stock rose immensely during the last few years as an assistant with his work with quarterbacks.Hell have his hands full in Miami, where his QB expertise will be needed to further the development of Ryan Tannehill, who has a big arm and a big contract, but has yet to post a winning record in four seasons. He has thrown for more than 4,000 yards each of the last two seasons, but has been inconsistent.Whether the Dolphins have gotten their offensive line fixed, so that Tannehill isnt under pressure all the time, is another major question.REXS WRECK: It has been a rough summer for Rex Ryans Bills, who might have finally found a bona fide starter in quarterback Tyrod Taylor, but have huge issues on defense.Ryan fully revamped the unit after it underperformed last year, but the Bills two top draft picks are injured. Outside linebacker Shaq Lawson, a first-rounder, had shoulder surgery in May and is expected to miss at least the first month of the season. Buffalos second-rounder, inside linebacker Reggie Ragland, is out for the season with a knee injury.Starting defensive tackle Marcell Dareus will also miss the first four games of the season for violating the NFLs substance abuse policy for a second consecutive year.PREDICTED ORDER OF FINISH: Patriots, Jets, Dolphins, Bills.---AP Sports Writers Kyle Hightower, John Wawrow and Steven Wine contributed.---AP NFL website: www.pro32.ap.org and AP NFL Twitter feed: http://twitter.com/AP-NFL NFL Jerseys Cheap Authentic . "It doesnt get any better than that," Giambi said. "Im speechless." The Indians are roaring toward October. Giambi belted a two-run, pinch-hit homer with two outs in the ninth inning to give Cleveland a shocking 5-4 win over the Chicago White Sox on Tuesday night, keeping the Indians up with the lead pack in the AL wild-card race. Wholesale NFL Jerseys .2 billion agreement with Rogers Communications for the leagues broadcast and multimedia rights. http://www.wholesalejerseyschinastitched.com/ . R.J. Umberger scored twice to lead the Blue Jackets to a franchise-record for consecutive wins with a 5-3 victory Tuesday night over the Los Angeles Kings. Cheap Jerseys From China . - The Oakland Raiders re-signed offensive lineman Khalif Barnes on Friday. STELLENBOSCH, South Africa -- It seems the sports world just doesnt know what to do with an athlete like Caster Semenya.The South African runner, and others like her, may present one of the greatest dilemmas for the perception of fairness in sports.Athletes like Semenya with intersex conditions -- those that dont conform to standard definitions of male or female -- debunk any presumption that everyone fits neatly into those definitive categories in sports.According to sports scientist Ross Tucker, the biology isnt quite as simple as that.Semenyas story is well-known. As an 18-year-old newcomer at the 2009 world championships, she dominated the best womens 800-meter runners. The gap between her and the defending world champion, who finished second, was astounding. Semenya celebrated by showing off her bicep muscles, stoking a controversy sparked hours earlier by revelations that she had undergone sex verification tests.She was later sidelined for 11 months by world tracks governing body, the IAAF, and was only cleared to run again in 2010. She returned and won a silver medal in the 800 at the 2012 Olympics.Now 25 and the favorite for gold at the Rio Olympics, Semenya has been pursued by gender questions. But her case has never been about a man masquerading as a woman.Semenya is a woman because she says shes a woman, was legally recognized at birth as female, treated as female, and identified as female. Nobody can dictate to Semenya what gender she is.But since the 1950s, track and field has conducted sex testing to protect womens competitions, initially using very basic sexual anatomy tests, and later using chromosomes. The tests didnt work.Sex testing in sports should be about preventing an unfair advantage and, therefore, not about genitalia or chromosomes, which dont make athletes run faster, jump higher or throw farther.What does, according to the IAAF, is testosterone.The IAAF says testosterone is the most significant factor in athletic performance. Men, generally, have more testosterone than women. In 2011, the IAAF officially drew a line between men and women in terms of testosterone.The issue it sought to resolve was hyperandrogenism -- high levels of naturally occurring testosterone in some women that apparently gave them a competitive advantage.Tucker said research conducted by the IAAF showed six women with intersex conditions competed at the 2011 world championships. Joanna Harper, an expert on gender in sports and a consultant to the IAAF, thinks two female medalists at this years indoor world championships are probably intersex, and estimated 5-10 intersex athletes will compete in track and field at the Rio Olympics.Six years after Semenya was subjected to the IAAF tests, the lid was lifted on her situation in 2015. Thats when Indian sprinter Dutee Chand went to the Court of Arbitration for Sport -- the highest court in world sports -- and challenged the IAAF rules that regulated testosterone in hyperandrogenic women.The case forced the IAAF to publicly defend its rules that for hyperandrogenic women to be eligible to compete as women, their testosterone levels must be below a certain mark. It came down to a tiny measurement: how many nanomoles -- a billionth of a mole -- of testosterone a woman had per liter of blood. It couldnt be 10 nanomoles or more per liter, roughly the lower end of the male range. If it was 10 or higher, it had to be lowered.Harper said the testosterone levels of these hyperandrogenic women could be lowered either through the removal of internal testes or with hormone-suppressing medication.Former Olympic runner Bruce Kidd, a professor of physical education and an adviser to Chand, opposes the testosterone-limiting rule. Hee argues that the testosterone is natural in these women, and although men produce more of it, there is nothing to say that testosterone is a male hormone.ddddddddddddDutee and Caster are (competing) with their own chemicals, Kidd said. They are fully in keeping with the Olympic spirit of being true to yourself and playing without doping. So why are they being castigated for that? I think it is so unfair.Significantly, the IAAF accepted that its rules were basically discriminatory but were devised in search of a greater justice: fairness for womens track and field.Opponents of the testosterone rule pointed to the natural advantages of other athletes that arent regulated, such as Usain Bolts fast-twitch muscle fibers, Michael Phelps big wingspan and former cyclist Miguel Indurains huge lung capacity.Harper, who supports the testosterone-limiting rules, explained that sports competitions dont have categories for athletes with slow twitch, short arms or small lungs. But womens sports are protected because if they werent, there would be serious ramifications for Olympic qualification.Chand -- and by default, Semenya -- won an interim decision last year in the Court of Arbitration for Sport case, but on a different reasoning. The IAAF didnt have definitive evidence to show how much of an advantage the extra testosterone gave hyperandrogenic women. CAS gave the IAAF until July 2017 to provide the evidence needed to reinstate the rule, which wont be in place in Rio.The IAAF said it doesnt comment on individuals who were managed under its hyperandrogenism regulations, but it still believes in the rules. Work is ongoing to find evidence.Harper is involved in that process and expects to be an expert witness for the IAAF when the case returns to court.The best evidence might be provided right now by Semenya.Since the testosterone regulations were shelved, Semenya has won every major 800-meter race she entered this season -- running a personal best last month and the fastest time anywhere in seven years. Her best time this year is around four seconds faster than last year.Tucker predicted it.At the start of the season, when Semenya was competing at the South African national championships, Tucker posted a tweet saying she could break Jarmila Kratochvilovas 33-year-old world record of 1:53.28 for the 800 this season. He thinks that without testosterone regulation, Semenya, a good athlete anyway, could become untouchable.You need a person who comes along and has got all the attributes that would make an elite athlete, plus they have high testosterone. Then you will get a freakishly good athlete, and thats the case with Semenya, Tucker said. If I was a woman 800-meter runner right now, Id be looking to change careers. You cant beat this advantage. Its too big.But Alice Dreger, a historian of medicine and science who has written about Semenya, poses a question with regard to the testosterone regulations and what the IAAF is trying to achieve with its proposed limits:The data they have indicates it causes the athletes performance to drop precipitously, basically eliminating them from play, Dreger said. So what does it really mean to say `you can compete if you get these interventions, if the interventions mean you cant really compete anymore?Semenya, often media-shy, smiled and spoke easily with reporters at the nationals, saying she was starting to enjoy the sport again.I havent had fun, you know, in a while, she said.---Follow Gerald Imray on Twitter: www.twitter.com/GeraldImrayAP---Follow the Rio de Janeiro Games at http://www.summergames.ap.org/ Cheap Stitched Jerseys China NFL Jerseys White Wholesale NFL Autographed Jerseys Jerseys From China Cheap NFL Jerseys Wholesale China Jerseys Wholesale Cheap Nike NFL Jerseys Cheap NFL Jerseys Wholesale NFL Jerseys Youth NFL Jerseys Cheap Wholesale NFL Gear Youth NFL Jerseys Wholesale Jerseys Wholesale Wholesale Nike NFL Jerseys Wholesale Nike NFL Jerseys ' ' '